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Heavy Metals:  Sources of Exposure and Target Organs

  Arsenic
Arsenic is released into the environment through production of copper, zinc, lead, chemicals and glasses. Arsenic is found in water supplies worldwide, leading to exposure of shellfish, cod, and haddock. Other sources are paints, rat poisoning, fungicides, and wood preservatives. The target organs for arsenic are the blood, kidneys, central nervous system, digestive system and skin.

Lead
Lead is a very soft metal and was used in pipes, drains, and soldering materials for many years. Millions of homes built before 1940 still contain lead leading to chronic exposure. Industry produces about 2.5 million tons of lead annually. Most of this lead is used for batteries. The remainder is used for cable coverings, plumbing, ammunition, fuel additives, paint pigments, PVC plastics, x-ray shielding, crystal glass production, pencils and pesticides. The target organs are the bones, brain, blood, kidneys, and thyroid gland.

Mercury
Mercury exists in three forms: elemental mercury, organic and inorganic mercury. Mining operations, chloralkali plants and paper industries are significant producers of mercury. Atmospheric mercury accumulates in aquatic food chains contaminating fish. Mercury continues to be used in thermometers, thermostats, dental amalgam fillings and vaccines. Inhalation is the most frequent route of exposure to mercury. The organic form is readily absorbed in the gastrointestinal tract (90-100%); lesser but still significant amounts of inorganic mercury are absorbed in the gastrointestinal tract (7-15%). The target organs are the brain and kidneys.

Cadmium
Cadmium is a byproduct of the mining and smelting of lead and zinc.  It is used in nickel-cadmium batteries, PVC plastics and paint pigments. Insecticides, fungicides, sludge and commercial fertilizers that use cadmium contaminate farmland. Cigarettes also contain cadmium. Lesser-known sources of exposure are dental alloys, electroplating, motor oil and exhaust. The target organs are the liver, placenta, kidneys, lungs, brain and bones.

 



 

 

 

 

 
 

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